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Nizam College established in 1887 is now 120 years old. Its founder was the eminent Dr. Aghorenath Chattopadhyaya, DSc (Edin.) . This college came into existence through the amalgamation of Hyderabad School (Nobel School) and Madrasa-I-Aliya . Mr.P.H. Hodson was its first British Principal.
Nizam College is considered as a miniature of the Hyderabad of yesteryears and the Andhra Pradesh of today. It has several firsts to its credit,Although a constituent conllege of Osmania University in view of its high degree of the academic performance Nizam College was conferred academic autonomy in 1988-89 at the undergraduate level. Academic autonomy became operational from 1989-90 by the directive of the University. Under autonomy the college is empowered to form its own syllabi, introduce new courses or combinations, and conductexaminations including setting of the question papers, valuation and declaration of the results at the undergraduate level.