Diploma in System Biology

Bharathiar University
In Coimbatore

Price on request
You can also call the Study Centre
42224... More
Compare this course with other similar courses
See all

Important information

  • Diploma
  • Coimbatore
Description

Goals: To understand the gradual maturation of genomics and proteomics into biology insilico. Convergence of genomics, proteomics, transcriptomics and metabolomics in to phenomics. Objectives: Students should be able to understand the interaction within biological networks and. simulation of cells.

Important information
Venues

Where and when

Starts Location
On request
Coimbatore
Bharathiar University, Coimbatore, 641046., Tamil Nadu, India
See map

Course programme

Subject description :
Includes the basics of analysing metabolic pathways using bioinformatics tools and also the
simulation of cellular environment.
Goals:
To understand the gradual maturation of genomics and proteomics into biology insilico.
Convergence of genomics, proteomics, transcriptomics and metabolomics in to phenomics.
Objectives:
Students should be able to understand the interaction within biological networks and
simulation of cells.
UNIT - I
Introduction to Systems biology What is Systems Biology? Integrating Networks.
Methods of study: Micro array - definition, types of array, Micro array analysis:
Hierarchical clustering, Self-organizing maps. Applications of Micro Arrays in systems
biology.
UNIT - II
Metabolomics & Metabolic Pathways
Digestion of proteins and protein metabolism, Transport metabolism, Carbohydrate
metabolism - metabolism of glucose - glycolysis, TCA cycle, glycogenesis, Pentose
phosphate shunt, Electron transport, Interconnection of pathways, metabolic regulation.
Translating biochemical networks into linear algebra.
UNIT - III
Whole cell simulation: Principle and levels of simulation - Virtual
Erythrocytes, Pathological analysis. Flux Balance Analysis
UNIT IV
Relationship analysis: Predicting ligand-binding function, Use of gene cluster, detecting
protein - protein interaction.
UNIT - V
Creative Bioinformatics: Novel use for database. Use of EST database - Unigene, gene
discovery, Primer design, Restriction mapping, Position specific cloning, SNP database,
Target identification, Epitope identification.

Compare this course with other similar courses
See all