DM [Oncology]

MAHARASHTRA UNIVERSITY OF HEALTH SCIENCES
In Nashik

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  • Nashik
Description

Important information
Venues

Where and when

Starts Location
On request
Nashik
Vani Road, Mhasrul, Nashik , 422004, Maharashtra, India
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Course programme

DM [Oncology]

Curriculum
I. Practical Laboratory Training
A. General Hematology and Oncology
1. Proper use and care of common instruments such as light microscope, centrifuge,
water baths, freezers etc.
2. Blood sample collection - venepuncture and finger prick methods of sample
collection, types of anticoagulants, containers and the effects of delay in processing
and storage.
3. Review of normal and abnormal blood films with emphasis on morphology of red
cells, white cells and platelets.
4. Performance of bone marrow aspiration; trephine needle biopsy
5. Staining and diagnostic evaluation of bone marrow aspirates. Interpretation of
cytochemical stains including Sudan Black, Myleloperoxidase, specific and non
specific esterases, acid phosphatase, PAS and iron staining.
B. Cytogenetics
Familiarisation with cytogenetics, understanding the principles of cytogenetics and
appreciating the relevance and significance of chromosomes in diagnostic hematology
and oncology
C. Transfusion Medicine
1. Donor evaluation & recruitment.
2. Clinical evaluation and screening of patients and donors for hematopoietic
stem cell transplantation.
3. Phlebotomy of donors.
4. Collection, cryopreservation and storage of hematopoietic stem cells.
D. Flow Cytometery
A working knowledge of the principle and practice of flowcytometery and
interpretation of the clinical significance of common leukocyte immunophenotypes.
E. Molecular Biology Module
Understanding the principles involved in the molecular diagnosis of hematological and
oncological disorders.
1. PCR
2. FISH
3. RFLP and Southern Blotting.
4. Microarray technology
II. Clinical Oncology Training
With appropriate guidance and under supervision, the post graduate trainee will be
responsible primarily for the acquisition of knowledge in all areas of oncology. Such
knowledge will be acquired and demonstrated through seminars, case presentations,
journal clubs, tutorials and proper use of library for suggested reading and formal reviews
of major selected topics. Faculty staff should be present at these various exercises so as
to provide the appropriate inputs. When necessary faculty staff may be required to review
certain subjects in form of formal lectures. Clinical experience will be acquired by the
trainee by day to day management of all patients admitted to the various oncology
services. Faculty will also be involved in teaching of trainees in the ward-rounds and
outpatient clinics.
COURSE CONTENTS
CANCER BIOLOGY
Molecular Biology
Cell Proliferation, Differentiation, and Apoptosis
Growth Factor Signal Transduction in Cancer
Oncogenes
Tumor Suppressor Gene Defects in
Recurring Chromosome Rearrangements in Human Cancer
Biochemistry of Cancer
Invasion and Metastases
Tumor Angiogenesis
TUMOR IMMUNOLOGY
Tumor Immunology
CANCER ETIOLOGY
Genetic Predisposition to Cancer
Chemical Carcinogenesis
Hormones and the Etiology of Cancer
Ionizing Radiation
Ultraviolet Radiation Carcinogenesis
Physical Carcinogens
Trauma and Inflammation
Tumor Viruses
Herpesviruses
Papillomaviruses and Cervical Neoplasia
Hepatitis Viruses
Parasites
CANCER EPIDEMIOLOGY
Cancer Epidemiology
THEORY AND PRACTICE OF CLINICAL TRIALS
Theory and Practice of Clinical Trials
CANCER PREVENTION
Prevention of Tobacco-Related Cancers
Nutrition in the Etiology and Prevention of Cancer
Chemo-prevention of Cancer
Cytokinetics
Drug Resistance and its Clinical Circumvention
Principles of Dose, Schedule, and Combination
Chemotherapy
Regional Chemotherapy
Animal Models in Developmental Therapeutics
In Vitro and In Vivo Predictive Tests
Pharmacology
Toxicology by Organ System
CHEMOTHERAPEUTIC AGENTS
Folate Antagonists
Pyrimidine and Purine Antimetabolites
Alkylating Agents and Platinum Antitumor Compounds
Anthracyclines and DNA Intercalators /
Epipodophyllotoxins / DNA Topoisomerases
Microtubule-Targeting Anticancer Drugs Derived from Plants and Microbes: Vinca
Alkaloids, Taxanes, and Epothilones, Asparaginase
PRINCIPLES OF ENDOCRINE THERAPY
Steroid Hormone Binding and Hormone Receptors
Hypothalamic and Other Peptide Hormones
Corticosteroids
Estrogens and Antiestrogens
Clinical Use of Aromatase Inhibitors in Breast Carcinoma
Progestins
Androgen Deprivation Strategies in the Treatment of Advanced Prostate Cancer
CANCER SCREENING AND EARLY DETECTION
Cancer Screening and Early Detection
PRINCIPLES OF CANCER PATHOLOGY
Principles of Cancer Pathology
PRINCIPLES OF IMAGING
a. Imaging Cancer of Unknown Primary Site
b. Imaging Neoplasms of the Head and Neck and Central
Nervous System
c. Imaging Neoplasms of the Thorax
d. Imaging Neoplasms of the Abdomen and Pelvis
e. Cross-Sectional Imaging of Musculoskeletal
Neoplasms
f. Imaging the Breast
g. Ultrasound in Cancer Medicine
h. Radionuclide Imaging in Cancer Medicine
i. Perspectives in Imaging
Interventional Radiology for the Cancer Patient
PRINCIPLES OF SURGICAL ONCOLOGY
Principles of Surgical Oncology
Vascular Access in Cancer Patients
PRINCIPLES OF RADIATION ONCOLOGY
Physical and Biologic Basis of Radiation Oncology
Principles of Hyperthermia
Photodynamic Therapy of Cancer
PRINCIPLES OF MEDICAL ONCOLOGY
Principles of Medical Oncology
PRINCIPLES OF BIOTHERAPEUTICS
Immunostimulants
Active Specific Immunotherapy with Vaccines
Interferons
Cytokines: Biology and Applications in Cancer Medicine
Hematopoietic Growth Factors .
Monoclonal Serotherapy
Cancer Gene Therapy
PRINCIPLES OF BONE MARROW
TRANSPLANTATION
Autologous Bone Marrow and Stem Cell Transplantation
Transplantation of Allogeneic Hematopoietic Cells for the Treatment of Malignancies
The student must be familiar with current indications and results of bone marrow
transplantation in various diseases.
1. Donor selection
HLA typing and MLR in bone marrow transplantation, screening of Donor
2. Conditioning regimens
the trainee must be familiar with the different conditioning regimens, principles of their
use in different disorders and complications
3. Harvesting and manipulation of the bone marrow
Bone marrow collection, red cell or plasma reduction, peripheral blood stem cell
mobilization and collection, cryopreservation, Transfusion of marrow. Purging of
marrow -T cell depletion.
3. Transplantation immunology
Histocompatibility, graft versus host disease - diagnosis and management. Immune
reconstitution following transplantation.
4. Management of post transplant patient
PRINCIPLES OF PSYCHO-ONCOLOGY
PRINCIPLES OF ONCOLOGY NURSING
Principles of Oncology Nursing
PRINCIPLES OF CANCER REHABILITATION MEDICINE
Principles of Cancer Rehabilitation Medicine
PRINCIPLES OF MULTIDISCIPLINARY MANAGEMENT
Principles of Multidisciplinary Management Palliative Care
PRINCIPLES OF SOCIETAL ONCOLOGY
Ethical Aspects of Caring for Patients with Cancer
Legal Aspects of Cancer
The Government and Cancer Medicine
Clinical Oncology in a Changing Health Care Environment
Outcomes Assessment
NEOPLASMS OF THE CENTRAL NERVOUS SYSTEM
Neoplasms of the Central Nervous System
NEOPLASMS OF THE EYE
Neoplasms of the Eye
NEOPLASMS OF THE ENDOCRINE GLANDS
Pituitary Neoplasms
Neoplasms of the Thyroid
Neoplasms of the Adrenal Cortex
Neoplasms of the Neuroendocrine System and
Neoplasms of the Gastroenteropancreatic
Endocrine System
NEOPLASMS OF THE HEAD AND NECK
Head and Neck Cancer
Odontogenic Tumors
NEOPLASMS OF THE THORAX
Cancer of the Lung
Malignant Mesothelioma
Thymomas and Thymic Tumors
NEOPLASMS OF THE FEMALE
REPRODUCTIVE ORGANS
Neoplasms of the Vulva and Vagina
Neoplasms of the Cervix
Endometrial Cancer
Neoplasms of the Fallopian Tube
Ovarian Cancer
Gestational Trophoblastic Disease
Gynecologic
NEOPLASMS OF THE BREAST
Neoplasms of the Breast
NEOPLASMS OF THE SKIN
Neoplasms of the Skin
MALIGNANT MELANOMA
Malignant Melanoma
NEOPLASMS OF THE BONE AND
SOFT TISSUE
Bone Tumors & Sarcomas of Non-osseous Tissues
NEOPLASMS OF THE HEMATOPOIETIC
SYSTEM
Myelodysplastic Syndrome
Acute Myeloid Leukemia in Adults
Chronic Myeloid Leukemia
Acute Lymphocytic Leukemia in Adults
Chronic Lymphocytic Leukemia
Tumors of the Heart and Great Vessels
Primary Germ Cell Tumors of the Thorax
Metastatic Tumors in the Thorax
Hairy-Cell Leukemia
Hodgkin's Disease


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