The main campus of Govt. Ayurveda College is at Puthiyakavu, two kilometers from Tripunithura town in the Vaikom Road. The place is named after the Durga temple (puthiya-new; kavu-temple) famous for the fire works display during the annual festival. It was a border area in between Cochin and Travancore the erstwhile princely States before the independence of India. The old building of the toll collection centre is still seen in the roadside. On Pathamudayam (the tenth day after Vishu, April 14 or 15) free trade is allowed in the forenoon, which is still re-enacted. Lack of infrastructure for the introduction of Degree course in Ayurveda prompted the authorities to shift the college to a land with more area. Thus in 1964 a land area of more than 11 acres was acquired for the college at Puthiyakavu and the foundation stone was laid in 1968 by the then Health Minister Sri. B.Wellington.