Post M.Sc Diploma in Genetic Engineering and Bioprocess DevelopmentThe Maharaja Sayajirao University of Baroda
Price on request
- Post Graduate Diploma
Frequent Asked Questions
Minimum 50% marks in M.Sc with Microbiology/Biotechnology/ Biochemistry/allied branches of biological sciences. Selection to the course shall be based on an Entrance Test and Viva voce (interview)
Paper I : General Microbiology and Immunology
Unit 1 : Introduction to Microbiology, Microbial diversity with representative examples, structure and organization of microbial cells, Microbiology in the environment : water and sewage, air, environmental pollution and biodegradation.
Unit 2 : Microbial physiology and biochemistry, Aerobic and anaerobic growth, microbial nutrition, growth kinetics, microbiological methodology with reference to special metabolic pathways and emphasis on industrial applications.
Unit 3 : Medical microbiology and immunology, Microbiology in human disease, introduction to immunology, basic immunological techniques, immunodiagnostic methods with examples of applications, monoclonal antibodies.
Paper II : Principles of Genetic Engineering
Unit 1 : Structure and properties of DNA/RNA, Hybridization techniques, introduction to molecular biology : basics of gene organization, transcription, translation and replication.
Unit 2 : Basics of bacterial and fungal genetics, methods in microbial genetics : mutagenesis and screening, strain improvement, transgenic plants and animals.
Unit 3 : Principles of cloning, introduction to cloning vectors, construction of genomic and cDNA libraries, PCR and DNA-based diagnostic techniques. DNA sequencing, Site directed mutagenesis, protein structure - function, relationship.
Paper III : Bioprocess Technology
Unit 1 : Raw materials for bioprocessing, comparison of chemical and biochemical processing based on energetics and environmental issues. Development of inocula, kinetics of enzymatic and microbial processes, optimisation studies, sterilization of media, air and equipment, modes of cell cultivation, general principles of bioreactor design and their operation.
Unit 2 : Downstream processing, separation and purification techniques, quality assurance testing, representative examples of microbial products, vaccines and vaccine development, immobilization of cells and enzymes : principles, methodology and applications, disintegration of cells, separation of solid and liquid phases, isolation and purification techniques for proteins and other products based on different physico-chemical properties, eg., precipitation, adsorption, chromatographic separations, bio-affinity based methods.
Unit 3 : Principles of bioprocess control, bioprocess automation and application of computers in bioprocessing, recombinant products with representative examples, biosafety and environmental monitoring of GEMs, Introduction to patents, Intellectual Property Rights in Biotechnology.