M.Pharma (Pharmaceutical Chemistry)

Unit-I
UV-Visible Spectroscopy : Electromagnetic spectrum,
UV-visible range, structural features, absorption of radiant energy,
factors influencing absorption of radiant energy: Instrumentation–
single-beam spectrophotometer, double-beam
spectrophotometer, Assay methods, Applications in
pharmaceutical analysis.
Infrared Spectroscopy : Molecular vibrations, stretching
vibrations, bending vibrations, vibrational frequencies, factors
influencing vibrational frequencies, electronic effects,
Instrumentation—Single-monochromator IR-spectrophotometer,
experimental profile of IR-monochromator IR-spectrophotometer,
experimental profile of IR-spectroscopy: Quantitative analysis,
applications in the analysis of Pharmaceutical dosage forms,
qualitative interpretation of IR-spectra, Recent advances in IRspectroscopy,
Optical Rotatory Dispersion : Fundamental principles
of ORD, Cotton-effect curves–their characteristics and
interpretation, Octet rule and its applications, circular dichroism.

Unit-II
Nuclear Magnetic Resonance Spectroscopy : The
NMR-phenomenon viz. spinning nucleus, effect of an external
field, precessional motion, precessional frequency, energy
transition, chemical shift, 3H-NMR (Tritium NMR-spectroscopy),
13C-NMR-spectroscopy, 2D-NMR, interpretations of NMRspectrum,
instrumentation, applications in pharmaceutical
analysis.